College student Holly Teller (Elisabeth Harnois) is drawn to the mysterious small town of Riddle, Pennsylvania in search of her missing brother. Against the will of the local Sheriff (Val Kilmer) and town elder (William Sadler), she begins to unravel a mystery connected to an abandoned psychiatric hospital on the edge of town, uncovering a terrifying past the town in determined to keep hidden.

The haunted Captain of a Soviet submarine holds the fate of the world in his hands. Forced to leave his family behind, he is charged with leading a covert mission cloaked in mystery.

Syd March is an employee at a clinic that sells injections of live viruses harvested from sick celebrities to obsessed fans. Biological communion – for a price. Syd also supplies illegal samples of these viruses to piracy groups, smuggling them from the clinic in his own body. When he becomes infected with the disease that kills super sensation Hannah Geist, Syd becomes a target for collectors and rabid fans. He must unravel the mystery surrounding her death before he suffers the same fate.